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个人简介
Dr. Pierre Rustin is interested in the understanding and the curing of mitochondrial diseases, in particular those linked to respiratory chain deficiency. Respiratory chain defects can lead to superoxide overproduction and cardiomyopathy as in diseases linked to complex I deficiency and Friedreich ataxia. The specific know-how of the group is our ability through biochemical approaches (spectrophotometry and polarography) to detect mild defects of the respiratory chain and Krebs cycle. As it has been shown that oxidative stress is widely involved in cardiovascular disease, we also focus our attention on the pathways regulating the response to oxidative stress insult. We study different models ranging from patients fibroblasts to mouse models with the objective to propose therapies.
研究兴趣
论文共 467 篇作者统计合作学者相似作者
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Khaled Tighanimine, José Américo Nabuco Leva Ferreira Freitas, Ivan Nemazanyy, Alexia Bankolé, Delphine Benarroch-Popivker, Susanne Brodesser,Gregory Doré, Lucas Robinson,Paule Benit,Sophia Ladraa,Yara Bou Saada,Bertrand Friguet,
crossref(2023)
Mügen Terzioglu, Kristo Veeroja, Toni Montonen,Teemu O Ihalainen,Tiina S Salminen,Paule Bénit,Pierre Rustin, Young-Tae Chang, Takeharu Nagai,Howard T Jacobs
eLife (2023)
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Kenza Nedara, Camille Reinhardt, Emilie Lebraud,Giuseppe Arena, Céline Gracia,Valérie Buard, Catherine Pioche-Durieu,Florence Castelli,Benoit Colsch,Paule Bénit,Pierre Rustin, Benoit Albaud,
M. Sanson,A. Vu Hong,E. Massourides, N. Bourg, L. Suel,F. Amor,G. Corre,P. Bénit,I. Barthélémy,S. Blot, A. Bigot, C. Pinset,
Nathalie Journiac,Javier Gilabert-Juan,Sara Cipriani,Paule Benit, Xiaoqian Liu,Sandrine Jacquier,Valérie Faivre,Andrée Delahaye-Duriez,Zsolt Csaba, Tristan Hourcade, Eliza Melinte,Sophie Lebon,
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