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个人简介
My lab has focused on understanding the mechanisms that determine whether T cells are activated or tolerized in vivo. We use a variety of transgenic and gene knock out mouse models to evaluate the molecular pathways that govern T cell fate. In particular, we examine how to promote T cell responses to tissues, with a goal to understand and control autoimmune and anti-tumor immune responses.
Our recent studies have examined novel ways that dendritic cells are programmed to influence T cell function in vivo. In addition we are focussed on how the tissue or tumor microenvironment can have a significant impact on T cell responses.
Importantly, my interests have also expanded to establishing an immune therapy platform. My group has developed the ability to grow tumor infiltrating T cells and characterize their properties. We have also coordinated clinical trials and are building towards a comprehensive program in immune therapy.
Our recent studies have examined novel ways that dendritic cells are programmed to influence T cell function in vivo. In addition we are focussed on how the tissue or tumor microenvironment can have a significant impact on T cell responses.
Importantly, my interests have also expanded to establishing an immune therapy platform. My group has developed the ability to grow tumor infiltrating T cells and characterize their properties. We have also coordinated clinical trials and are building towards a comprehensive program in immune therapy.
研究兴趣
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Oncoimmunologyno. 1 (2024): 2349347-2349347
Eric Y. Stutheit-Zhao,Enrique Sanz-Garcia,Zhihui (Amy) Liu,Derek Wong,Kayla Marsh, Albiruni R. Abdul Razak,Anna Spreafico,Philippe L. Bedard,Aaron R. Hansen, Stephanie Lheureux,Dax Torti,Bernard Lam,
crossref(2024)
Eric Y. Stutheit-Zhao,Enrique Sanz-Garcia,Zhihui (Amy) Liu,Derek Wong,Kayla Marsh, Albiruni R. Abdul Razak,Anna Spreafico,Philippe L. Bedard,Aaron R. Hansen, Stephanie Lheureux,Dax Torti,Bernard Lam,
crossref(2024)
Mucosal Immunology (2024)
Eric Y. Stutheit-Zhao,Enrique Sanz-Garcia,Zhihui (Amy) Liu,Derek Wong,Kayla Marsh, Albiruni R. Abdul Razak,Anna Spreafico,Philippe L. Bedard,Aaron R. Hansen, Stephanie Lheureux,Dax Torti,Bernard Lam,
crossref(2024)
Eric Y. Stutheit-Zhao,Enrique Sanz-Garcia,Zhihui (Amy) Liu,Derek Wong,Kayla Marsh, Albiruni R. Abdul Razak,Anna Spreafico,Philippe L. Bedard,Aaron R. Hansen, Stephanie Lheureux,Dax Torti,Bernard Lam,
crossref(2024)
Eric Y. Stutheit-Zhao,Enrique Sanz-Garcia,Zhihui (Amy) Liu,Derek Wong,Kayla Marsh, Albiruni R. Abdul Razak,Anna Spreafico,Philippe L. Bedard,Aaron R. Hansen, Stephanie Lheureux,Dax Torti,Bernard Lam,
crossref(2024)
Eric Y. Stutheit-Zhao,Enrique Sanz-Garcia,Zhihui (Amy) Liu,Derek Wong,Kayla Marsh, Albiruni R. Abdul Razak,Anna Spreafico,Philippe L. Bedard,Aaron R. Hansen, Stephanie Lheureux,Dax Torti,Bernard Lam,
crossref(2024)
Eric Y. Stutheit-Zhao,Enrique Sanz-Garcia,Zhihui (Amy) Liu,Derek Wong,Kayla Marsh, Albiruni R. Abdul Razak,Anna Spreafico,Philippe L. Bedard,Aaron R. Hansen, Stephanie Lheureux,Dax Torti,Bernard Lam,
crossref(2024)
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