Patrizia Porazzi - Division of Hematology and Oncology and Center for Cellular Immunotherapies, University of Pennsylvania

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Career Trajectory

Bio

Patrizia Porazzi currently works at the Department of Cancer Biology (Sydney Kimmel Cancer Center), Thomas Jefferson University. Patrizia does research in Oncology and Leukemia. Her current project is 'The role of chromatin structure during development of HSCs and in targeting Acute Myeloid leukemia'.

Research Interests

Papers共 68 篇Author StatisticsCo-AuthorSimilar Experts

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Ketogenic Diet Enhances CAR T Cell Antitumor Function Via Β-Hydroxybutyrate

Shan Liu,Puneeth Guruprasad, Kecheng Han,Luca Paruzzo,Alexander Shestov,Andre Kelly, Kevin R. Amses, Amichay Afriat,Bhoomi Madhu,Lev Litichevskiy, Ezra Dubowitz, Neil Tangal,Alana McSween, Melody Tan,Alberto Carturan, Andrew Lee, Yunlin Zhang,Giulia Gabrielli,Raymone Pajarillo, Ruchi P. Patel,Guido Ghilardi,Patrizia Porazzi,Stephen J. Schuster,Roddy S. O'Connor,Michael C. Milone,Joshua Rabinowitz,Maayan Levy,Marco Ruella

Bloodno. Supplement 1 (2024): 4-4

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EZH1/2 Inhibition Improves the Anti-Tumor Efficacy of CAR and TCR T-Cell Based Therapies Against Multiple Liquid and Solid Tumors

Siena Nason, Ziqi Yang,Guido Ghilardi,Luca Paruzzo,Alberto Carturan,Eugenio Fardella,Puneeth Guruprasad, Anushka Anant Padmanabhan,Tatiana Blanchard,Gerald Linette,Beatriz M. Carreno,Sandra Susanibar-Adaniya,Alfred L. Garfall,Marco Ruella,Patrizia Porazzi

Bloodno. Supplement 1 (2024): 4792-4792

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EZH2 Inhibition Enhances T Cell Immunotherapies by Inducing Lymphoma Immunogenicity and Improving T Cell Function

Yusuke Isshiki,Xi Chen,Matt Teater,Ioannis Karagiannidis, Henna Nam, Winson Cai,Cem Meydan,Min Xia,Hao Shen,Johana Gutierrez, Vigneshwari Easwar Kumar, Sebastián E. Carrasco, Madhu M. Ouseph,Samuel Yamshon,Peter Martin,Ofir Griess,Efrat Shema,Patrizia Porazzi,Marco Ruella,Renier J. Brentjens

Cancer cell（2024）

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CD5 Deletion Enhances the Antitumor Activity of Adoptive T Cell Therapies

SCIENCE IMMUNOLOGYno. 97 (2024)

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The BTLA-HVEM Axis Restricts CAR T Cell Efficacy in Cancer

Puneeth Guruprasad,Alberto Carturan,Yunlin Zhang,Jong Hyun Cho,Kingsley Gideon Kumashie,Ruchi P. Patel,Ki-Hyun Kim,Jong-Seo Lee,Yoon Lee,Jong Hoon Kim,Junho Chung, Akshita Joshi,Ivan Cohen,Maksim Shestov,Guido Ghilardi,Jaryse Harris,Raymone Pajarillo,Mathew Angelos,Yong Gu Lee, Shan Liu,Jesse Rodriguez,Michael Wang,Hatcher J. Ballard,Aasha Gupta,Ositadimma H. Ugwuanyi,Seok Jae Albert Hong, Audrey C. Bochi-Layec, Christopher T. Sauter,Linhui Chen,Luca Paruzzo, Shane Kammerman,Olga Shestova,Dongfang Liu,Laura A. Vella,Stephen J. Schuster,Jakub Svoboda,Patrizia Porazzi,Marco Ruella

Nature Immunologyno. 6 (2024): 1020-1032

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Overcoming the Lack of CD2:CD58 Costimulation in Chimeric Antigen Receptor T-Cell Immunotherapies

Alberto Carturan,Mathew G. Angelos,Raymone Pajarillo,Jesse Rodriguez,Jaryse Harris, Yunlin Zhang, Ekta Singh, Andrew Lee,Ositadimma Ugwuanyi, Ruchi P. Patel,Puneeth Guruprasad,Jean Lemoine,Jong Hyun Cho,Patrizia Porazzi,Stephen J. Schuster,Marco Ruella

Bloodno. Supplement 1 (2024): 504-504

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Supplementary Table S1 from Targeting CDK6 and BCL2 Exploits the “MYB Addiction” of Ph<sup>+</sup> Acute Lymphoblastic Leukemia

Marco De Dominici,Patrizia Porazzi,Angela Rachele Soliera,Samanta A. Mariani,Sankar Addya,Paolo Fortina,Luke F. Peterson,Orietta Spinelli,Alessandro Rambaldi,Giovanni Martinelli,Anna Ferrari,Ilaria Iacobucci,Bruno Calabretta

crossref（2023）

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EZH2 Inhibitors Enhance CART Cell Quality, Efficacy, in Vivo Homing, Tumor Cell Binding and Killing of Fully Syngeneic Primary B Cell Lymphomas, As Well As Reprogramming Lymphoma Cells to a Highly Immunogenic and T Cell Adherent Phenotype

Yusuke Isshiki,Patrizia Porazzi,Xi Chen,Matthew Teater,Ioannis Karagiannidis, Henna S. Nam,Ari M. Melnick,Marco Ruella, Wendy Baguelin

BLOOD (2023)

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Apoptosis: Ajanus Bifronsin T-cell Immunotherapy

Yong Gu Lee, Nicholas Yang,Inkook Chun,Patrizia Porazzi,Alberto Carturan,Luca Paruzzo,C Sauter,Puneeth Guruprasad,Raymone Pajarillo,Marco Ruella

Journal for immunotherapy of cancerno. 4 (2023): e005967-e005967

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