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My research focuses on a characterization of the mechanism by which bacteria deliver DNA and protein effector molecules across their cell envelopes and into eukaryotic target cells. Many medically and agriculturally important pathogens elaborate macromolecular secretion machines, termed type IV secretion (T4S) systems, to deliver effector molecules across kingdom boundaries at specific stages of infection. Studies in my laboratory exploit a combination of molecular, genetic, and biochemical approaches to identify and compare structural and functional properties of T4S systems used by the plant pathogen, A. tumefaciens, and the human pathogens, E. faecalis and B. cenocepacia, to cause disease.
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论文共 143 篇作者统计合作学者相似作者
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Kouhei Kishida,Yang Grace Li, Natsumi Ogawa-Kishida,Pratick Khara, Abu Amar M. Al Mamun,Rachel E. Bosserman,Peter J. Christie
PLOS GENETICSno. 3 (2024): e1011088-e1011088
JOURNAL OF HAZARDOUS MATERIALS (2024): 132560-132560
SCIENCE OF THE TOTAL ENVIRONMENT (2024): 168389-168389
The Science of the total environment (2023): 167627-167627
bioRxiv : the preprint server for biology (2023)
The Science of the total environment (2023): 167216-167216
Chemosphereno. Pt 2 (2022): 131750-131750
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