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More importantly, his work established the foundations for the key role of catecholamines and other neurotransmitters in stress, the regulation of the central and peripheral sympathetic activity in acute and repeated stress, as well as mechanisms of adaptation and the pathological consequences of loss of homeostasis. The focus of his research adapted to the continuous scientific innovations included an increasing consideration of basic molecular interactions, the use of state-of-the-art transgenic and knock-out models, and more recently a focused evaluation of the effects of chronic stress on neurodegenerative disorders. Thus, Richard’s work not only pioneered the field of stress research, but also made fundamental contributions of major translational value.
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STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESSno. 4 (2016): 439-447
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