基本信息
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职业迁徙
个人简介
Wolf Reik is a molecular biologist who has made a series of spectacular discoveries relating to the control system — known as epigenetics — that normally ensures the stable expression of our genes. His work revealed that these mechanisms depend on the addition of simple compounds called methyl groups to a proportion of the adenine and cytosine bases that make up half of our DNA.
Wolf also discovered that mammalian eggs, sperm and embryos undergo extensive epigenetic reprogramming as methyl groups are stripped away and reattached. This can be affected by factors in the environment, so that the consequences of these exposures can pass from one generation to another.
Currently Wolf is exploring how global reprogramming enables stem cells to adopt a variety of adult identities. These insights may lead to better strategies for regenerative medicine, using stem cells to repair diseased tissues, and also to better understanding of the ageing process.
研究兴趣
论文共 452 篇作者统计合作学者相似作者
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Pranay Shah, Ross James Hill,Stephen Clark,Camille Dion,Abdulkadir Abakir,Mark Arends,Harry Leitch,Wolf Reik,Gerry Crossan
Research Square (Research Square) (2023)
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Luke Harland, Bart Theeuwes, Alexandra Bisia,Mai-Linh Ton,Ricard Argelaguet,Stephen Clark,Tim Lohoff,Nicola Wilson,Wolf Reik, Elizabeth Robertson,Bertie Gottgens
EXPERIMENTAL HEMATOLOGY (2023): S89-S89
Oana Nicoleta Kubinyecz,Deborah Drage, Maria de Fatima Santos Constancia, Christel Krueger,Hanneke Okkenhaug, Jasmin Taubenschmid-Stowers,Wolf Reik
biorxiv(2023)
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Joao Agostinho de Sousa,Chee-Wai Wong, Ilona Dunkel, Thomas Owens, Philipp Voigt, Adam Hodgson,Duncan Baker, Edda G. Schulz,Wolf Reik,Austin Smith,Maria Rostovskaya,Ferdinand von Meyenn
Current Opinion in Genetics & Development (2023): 102066-102066
Sally Martin,Daniel Poppe,Nelly Olova, Conor O'Leary,Elena Ivanova,Jahnvi Pflueger, Jennifer Dechka,Rebecca K Simmons,Helen M Cooper,Wolf Reik,Ryan Lister,Ernst J Wolvetang
Genesno. 5 (2023)
Nature Chemical Biologyno. 8 (2023): 932-933
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Jan Vijg,Björn Schumacher,Abdulkadir Abakir, Michael Antonov, Chris Bradley,Alex Cagan,George Church,Vadim N Gladyshev,Vera Gorbunova,Alexander Y Maslov,Wolf Reik, Samim Sharifi,
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