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个人简介
Tsien contributed to the fields of cell biology and neurobiology by discovering genetically programmable fluorescent tags, thereby allowing scientists to watch the behavior of molecules in living cells in real time. He also developed fluorescent indicators of calcium ions and other ions important in biological processes.
In 2004, Tsien was awarded the Wolf Prize in Medicine "for his seminal contribution to the design and biological application of novel fluorescent and photolabile molecules to analyze and perturb cell signal transduction.
In 2008, Tsien shared the Nobel Prize in Chemistry with Osamu Shimomura and Martin Chalfie for "the green fluorescent protein: discovery, expression and development.
Awards and honors
Roger Y. Tsien has received numerous honors and awards in his life, including:
National 1st Prize, Westinghouse Science Talent Search (1968)
National Merit Scholarship, USA (1968)
Detur Prize, Harvard College (1969)
Marshall Scholarship, British government (1972)
Comyns Berkeley Research Fellowship, Gonville and Caius College, Cambridge (1977)
Gedge Prize, University of Cambridge (1978)
Searle Scholar, Searle Scholar program (1983)
Lamport Prize, New York Academy of Sciences (1986)
Javits Neuroscience Investigator Award, National Institute of Neurological Disorders and Stroke (1989)
Young Scientist Award, Passano Foundation (1991)
W. Alden Spencer Award in Neurobiology, Columbia University (1991)
Artois-Baillet-Latour Health Prize, Belgium (1995)
Gairdner Foundation International Award, Canada (1995)
Basic Research Prize, American Heart Association (1995)
Elected to the United States Institute of Medicine (1995)
Doctorate honoris causa, Katholieke Universiteit Leuven, Belgium (1995)
Faculty Research Lecturer, UC San Diego (1997)
Elected to the American Academy of Arts and Sciences (1998)
Elected to the United States National Academy of Sciences (1998)
Award for Innovation in High Throughput Screening, Society for Biomolecular Screening (1998)
Pearse Prize, Royal Microscopical Society (2000)
ACS Award for Creative Invention, American Chemical Society (2002)
Christian B. Anfinsen Award, Protein Society (2002)
Heineken Prize for Biochemistry and Biophysics, Royal Netherlands Academy of Arts and Sciences (2002)
Max Delbrück Medal, Max Delbrück Centrum für Molekulare Medizin, Berlin (2002)
Wolf Prize in Medicine, Israel (2004)
Keio Medical Science Prize, Japan (2004)
UCSD Chancellor's Associates Award for Excellence in Science & Engineering Research, UC San Diego (2004)
Perl-UNC Neuroscience Prize, University of North Carolina (2004)
Associate EMBO Member of the European Molecular Biology Organization 2005.
J.Allyn Taylor International Prize in Medicine, Robarts Research Institute, Canada (2005)
ABRF Award, Association of Biomolecular Resource Facilities (2006)
Lewis S. Rosenstiel Award for Distinguished Work in the Basic Medical Sciences, Brandeis University (2006)
Elected a Foreign Member of the Royal Society (ForMemRS) in 2006
BioPharma Leadership Award, the 6th Annual San Diego BioPharma Conference, San Diego (2007)
US Department of Defense (DoD) Breast Cancer Innovator Award
Nobel Prize in Chemistry, Sweden (2008)
E.B. Wilson Medal, American Society for Cell Biology (2008)
Honorary Fellow of the Royal Society of Chemistry (HonFRSC), UK (2008)
Honorary Academician, Academia Sinica (2008)
February 18, 2009, Roger Tsien Day, in the City of San Diego, California, USA
Distinguished Science and Technology Award, The 2009 Asian American Engineers of the Year (AAEoY) Award (April 2009)
Lifetime Innovation Award, UC San Diego (May 20, 2009)
AHA Distinguished Scientists, American Heart Association (2009)
Molecular Imaging Achievement Award, Society of Molecular Imaging (2009)
Doctor of Science honoris causa, The University of Hong Kong (2009)
Doctor of Science honoris causa, Chinese University of Hong Kong (2009)
General President Gold Medal, the 97th Indian Science Congress, India (January 3, 2010)
Spiers Memorial Award, Royal Society of Chemistry, UK (2010)
Golden Goose Award (2012)
Golden Plate Award of the American Academy of Achievement (2012)
研究兴趣
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Oral oncology (2017): 156-162
Rodriguez, Erik A,Tran, Geraldine N, Gross, Larry A, Crisp, Jessica L,Shu, Xiaokun,Lin, John Y,Tsien, Roger Y
Stephen R. Adams, Howard C. Yang,Elamprakash N. Savariar, Joe Aguilera,Jessica L. Crisp,Karra A. Jones,Michael A. Whitney,Scott M. Lippman,Ezra E. W. Cohen,Roger Y. Tsien,Sunil J. Advani
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