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The regulation of assimilatory sulfate reduction and biosynthesis of cysteine is investigated using the favorite plant of molecular biologists, Arabidopsis thaliana, a member of the Brassicaceae family. Cysteine is of great importance for human and animal nutrition. It is the precursor of donor for all compounds containing reduced sulfur in the cell. Sulfur is indispensable for proteins (methionine, disulfide bridges), electron transport (Fe/S clusters), redox control (glutathione) and cofactors (acetyl coenzyme A, biotin, thiamine, lipoic acid). In plants it additionally contributes to plant defense and secondary metabolism. Reduced sulfur is therefore an indispensable factor for life. Plants as photoautotrophic organisms are, directly or indirectly, the exclusive source of cysteine for animal life.
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Xiaodi Gong,Jean -Baptiste Boyer, Simone Gierlich, Marlena Pozoga,Jonas Weidenhausen,Irmgard Sinning,Thierry Meinnel,Carmela Giglione,Yonghong Wang,Ruediger Hell,Markus Wirtz
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PLANT JOURNALno. 1 (2023): 127-138
Journal of experimental botanyno. 11 (2023): 3379-3394
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Hagen Gegner,Thomas Naake,Karim Aljakouch,Aurelien Dugourd,Georg Kliewer, Torsten Mueller, Dustin Schilling,Marc Andre Schneider, Nina Kunze,Thomas G. P. Gruenewald,Ruediger Hell,Julio Saez-Rodriguez,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Eric Linster, Francy L. Forero Ruiz,Pavlina Miklankova,Thomas Ruppert, Johannes Mueller,Laura Armbruster,Xiaodi Gong,Giovanna Serino,Matthias Mann,Rüdiger Hell,Markus Wirtz
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