For the past 45 years he had an active role at the National Institutes of Health, first as a member of the Advisory Committee for the Artificial Kidney–Chronic Uremia Program, then as a member and chairman of General Medicine B and chairman of the Clinical Study on the Effect of Dietary Modification on the Course of Progressive Renal Disease.

Saulo played an active role in the National Kidney Foundation of Eastern Missouri and Metro East, and an annual lectureship was established in his honor in 1990. He also played a critical role in the development of the American Society of Nephrology, and in 1985 he became its president. He held numerous positions in the International Society of Nephrology and, since 1997, was a member of the Executive Committee. He was also an associate editor of the Journal of Clinical Investigation and the editor of the American Journal of Kidney Diseases and of Kidney International for many years.