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个人简介
Research Synopsis
Our research focuses on utilizing and developing tissue engineering approaches to address cardiovascular problems.
Motivated by the need to generate alternative therapeutic avenues to treat cardiovascular diseases and diabetes, I am interested in:
the development of vascularization strategies in combination with human stem cells for regenerative medicine;
the generation of complex, vascularized human tissues in vitro for cell biology studies and drug screening purposes;
understanding the nature and mechanistic basis of vessel maturation during adult neovascularization;
the coupled development of cardiomyocytes and vasculature, and;
promoting human stem cell-derived cardiomyocyte maturation through biomimetic approaches.
Our long-term goal is to develop innovative tools for regenerative medicine applications. Strategies include: transgenic animal models, stem cells, cell culture and bioengineering approaches.
Our research focuses on utilizing and developing tissue engineering approaches to address cardiovascular problems.
Motivated by the need to generate alternative therapeutic avenues to treat cardiovascular diseases and diabetes, I am interested in:
the development of vascularization strategies in combination with human stem cells for regenerative medicine;
the generation of complex, vascularized human tissues in vitro for cell biology studies and drug screening purposes;
understanding the nature and mechanistic basis of vessel maturation during adult neovascularization;
the coupled development of cardiomyocytes and vasculature, and;
promoting human stem cell-derived cardiomyocyte maturation through biomimetic approaches.
Our long-term goal is to develop innovative tools for regenerative medicine applications. Strategies include: transgenic animal models, stem cells, cell culture and bioengineering approaches.
研究兴趣
论文共 43 篇作者统计合作学者相似作者
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biorxiv(2022)
Kayla Soon,Mengyuan Li,Ruilin Wu, Angela Zhou, Negar Khosraviani, Williamson D Turner, Joshua D Wythe,Jason E Fish,Sara S Nunes
Yasaman Aghazadeh,Frankie Poon,Farida Sarangi,Frances T M Wong, Safwat T Khan,Xuetao Sun, Rupal Hatkar,Brian J Cox,Sara S Nunes,M Cristina Nostro
Shunsuke Funakoshi,Ian Fernandes, Olya Mastikhina, Dan Wilkinson,Thinh Tran,Wahiba Dhahri,Amine Mazine,Donghe Yang, Benjamin Burnett, Jeehoon Lee,Stephanie Protze,Gary D. Bader,
Xuetao Sun,Sara S Nunes
biorxiv(2021)
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