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个人简介
I joined the Opperman group in October 2017 on an Oxford-Celgene Research Fellowship, on a joint project with the Vyas group at the Weatherall Institute, where I am also a group member. Previously I studied undergraduate medicine in Cambridge, followed by Oxford for clinical medical training. My clinical haematology specialty training was also completed in Oxford.
My research on the Oxford-Celgene Fellowship concerns the tracking of myeloma resistance development to IMiD drugs, in cell lines and patient-donated samples at a single-cell level. By analysing mutational differences in clones and subclones of the tumour throughout disease progression, we aim to understand more about why it may respond but then relapse following different sequential therapies. We will integrate this approach with analysing changes in the composition of immune and other microenvironmental cell types, and their role in achieving disease remission.
My research on the Oxford-Celgene Fellowship concerns the tracking of myeloma resistance development to IMiD drugs, in cell lines and patient-donated samples at a single-cell level. By analysing mutational differences in clones and subclones of the tumour throughout disease progression, we aim to understand more about why it may respond but then relapse following different sequential therapies. We will integrate this approach with analysing changes in the composition of immune and other microenvironmental cell types, and their role in achieving disease remission.
研究兴趣
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Haematologica (2024)
Rebecca Bamford, Shayda Maleki-Toyserkani, Will Taverner, Jennifer A. Freedman, Michael J. Hayman, Manoj Saini,Sarah Gooding,Karthik Ramasamy, Kerry D. Fisher,Margaret R. Duffy
HemaSphereno. S3 (2023): e334939c-e334939c
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Lucia Y. Chen,Oliver Van Oekelen,Michael Amatangelo, Tracy T. Chow,Bhaskar Upadhyaya,Alessandro Lagana,Geoffrey Kelly,Seunghee Kim-Schulze,Adolfo Aleman, Antonina Kurtova,Sarah Gooding,Sundar Jagannath,
crossref(2023)
CANCER DISCOVERYno. 2 (2023): 364-385
Blood cancer journalno. 1 (2023): 12-12
Bloodno. Supplement 1 (2023): 644-644
Dipal Mehta,Laura Chiecchio,Martin F. Kaiser,Sarah Gooding,Kara-Louise Royle, Doina Levinte,Catherine Olivier,David Allan Cairns, Lorna Barnard,Sharon Jackson,Robert Cicero,Gordon Cook,
BLOODno. Supplement 1 (2023): 6715-6715
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