Sean Lawler

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Bio

He is affiliated with the Brown Cancer Center where he is co-leader of the CNS Cancer Translational Disease Research Group. The Lawler Lab investigates therapeutic approaches for the treatment of Brain Cancer, from preclinical models, to the analysis of data from patient tumors, with the goal of developing the next generation of therapeutic approaches for these extremely challenging diseases.

Research Interests

Papers共 356 篇Author StatisticsCo-AuthorSimilar Experts

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Identification of Transcriptomic Signatures Associated with Glioblastoma Recurrence

Sean E. Lawler

NEURO-ONCOLOGYno. 6 (2024): 989-990

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Onco-fetal Protein Nogo-A Restricts Human and Mouse Glioma Vascularization and Growth Via VEGF-Notch-hippo-metabolic Signaling

Marc Schwab,Moheb Ghobrial,Jorge Jimenez Macias,Michal Beffinger, Yanrong Ji, Andrin Wacker, Hidekiyo Harada,Jau-Ye Shiu, Oskar Novitzki,Ignazio De Trizio,Francesco Girolamo,Mariella Errede,Tobias Weiss,Dorothee Gramatzki, Miguel Maurer,Oliver Weinmann,Viola Vogel,Ivan Radovanovic, Martin Schwab,Nadia Dahmane,Jeffrey Greenfield,Antonio E Chiocca,Daniela Virgintino,Michael Weller,Johannes vom Berg,Johannes Vogel, Ramana V Davuluri,Karl Frei,Ralph Schlapbach,Katrien De Bock,Philippe p Monnier,Sean E Lawler,Thomas Walchli

biorxiv（2024）

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TMIC-45. CYTOMEGALOVIRUS PP65 ANTIGEN EXPRESSION FOLLOWING PP65-SPECIFIC DENDRITIC CELL VACCINATION IN MATCHED PRIMARY AND RECURRENT GLIOBLASTOMA SPECIMENS

Tarek Bou Dargham, Zuowei Su, Sergio Pina-Oviedo,Michael Brown,Sarah Cook, Diane Satterfield,Stevie Threatt, Weihua Xie,Pam Norberg,Mustafa Khasraw,Roger E McLendon,Gerald E Archer, John H Sampson, Duane A Mitchell,Charles Cobbs,Sean Lawler,Kristen Batich

Neuro-Oncologyno. Supplement_8 (2024)

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DIRECTIONALLY NON-ROTATING ELECTRIC FIELD THERAPY (DNEFT) DELIVERED THROUGH IMPLANTED ELECTRODES: A NOVEL SURGICAL PLATFORM FOR GLIOBLASTOMA IMMUNOTHERAPY

Jun Ma,Shilpi Singh, Ming Li, David Seelig,Gregory Molnar,Eric Wong,Sanjay Dhawan, Stefan Kim, Logan Helland, David Chen,Nikos Tapinos,Sean Lawler,Gatikrushna Singh,Clark Chen

NEURO-ONCOLOGY (2024)

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Exploring the Effects of Indirubins in Pediatric Diffuse High Grade Glioma Models

Jasmine S. Clark,Jorge Jimenez-Macias,Philippa Vaughn-Beaucaire,Shengliang Zhang,Wafik El-Deiry,Rishi Lulla,Sean Lawler

Cancer Researchno. 6_Supplement (2024): 5110-5110

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DDEL-13. ENHANCING THE EFFICACY OF THE BBB-PENETRANT PEPTIDE-DRUG CONJUGATE PT(IV)-M13 WITH THE KINASE INHIBITOR BIA TO IMPROVE INTRA-TUMORAL DELIVERY AND INHIBIT DNA REPAIR

Philippa Vaughn-Beaucaire,Jorge Luis Jimenez Macias, Edward Miller,Bradley Pentelute,Sean Lawler

Neuro-Oncologyno. Supplement_8 (2024)

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Intracranial CAR-T Cell Delivery in Glioblastoma Patients

Philippa Vaughn-Beaucaire,Moon Jung Choi,Olin Liang,Sean E. Lawler

Trends in cancerno. 6 (2024): 478-480

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Directionally Non-Rotating Electric Field Therapy Delivered Through Implanted Electrodes As a Glioblastoma Treatment Platform: A Proof-of-principle Study

Jun Ma,Shilpi Singh,Ming Li,Davis Seelig, Gregory F. Molnar,Eric T. Wong,Sanjay Dhawan, Stefan Kim, Logan Helland, David Chen,Nikos Tapinos,Sean Lawler,Gatikrushna Singh,Clark C. Chen

Neuro-Oncology Advancesno. 1 (2024)

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Blood-tumor Barrier Organoids Recapitulate Glioblastoma Microenvironment and Enable High-Throughput Modeling of Therapeutic Delivery

Choi-Fong Cho,Pei Zhuang,Benjamin Scott, Shuai Gao, Wei-Min Meng, Rui Yin, Xinyu Nie,Ludovica Gaiaschi,Sean E Lawler,Martine LM Lamfers,Fengfeng Bei

biorxiv（2024）

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ENHANCING THE EFFICACY OF THE BBB-PENETRANT PEPTIDE-DRUG CONJUGATE PT(IV)-M13 WITH THE KINASE INHIBITOR BIA TO IMPROVE INTRA-TUMORAL DELIVERY AND INHIBIT DNA REPAIR

Philippa Vaughn-Beaucaire,Jorge Luis Jimenez Macias, Edward Miller,Bradley Pentelute,Sean Lawler

NEURO-ONCOLOGY (2024)

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Associate Professor

Papers共 356 篇Author StatisticsCo-AuthorSimilar Experts