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Research in the Chemler group is focused on organic synthesis and catalysis for applications in medicinal chemistry, chemical biology and sustainability. A major area of research in the Chemler group is the discovery, development and synthetic application of enantioselective copper-catalyzed oxidative functionalizations of alkenes. Alkenes are a ubiquitous functional group and copper is an Earth abundant transition metal with significant catalytic versatility. Many of the products are chiral saturated nitrogen and oxygen heterocycles, compounds frequently found in bioactive small molecules.
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The Journal of organic chemistryno. 2 (2024): 1256-1263
ARKIVOCno. 2 (2024): 1-24
Rati Lama,Chao Xu,Samuel L Galster, Javier Querol-García,Scott Portwood,Cory K Mavis,Federico M Ruiz,Diana Martin,Jin Wu, Marianna C Giorgi,Jill Bargonetti,Eunice S Wang,
ACS CATALYSISno. 13 (2022): 7559-7564
Moleculesno. 22 (2022): 7665-7665
Organic Reactionspp.421-769, (2021)
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