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Research at Dr Jiang’s Laboratory focuses on understanding mechanisms of antigen presentation to the immune system; biomarker discovery and the development of new vaccines, including therapeutic vaccines with a particular emphasis on translating discoveries into new treatments for cancer patients. One major outcome of this work has been the development of a recombinant overlapping peptides technology for cancer therapeutic vaccines and diagnostics. This innovation has led to the formation of a spinout company, Oxford Vacmedix UK Ltd. Two candidates are close to clinical trials. Meanwhile the lab continues to focus on reaching an in-depth understanding of the immune pathways activated by ROPs and identifying additional targets that are amenable to the approach.
Another discovery at Dr Jiang’s Lab is a new biomarker, Inflammation Enhancer (IE). IE is an autoimmune disease factor - together with TNF, IE deteriorates inflammatory diseases such as sepsis and leads to high incidence of fatality. The lab is focusing on elucidating the pathway of IE that leads to inflammation. Diagnostic methods as well as treatments are also in development.
Another discovery at Dr Jiang’s Lab is a new biomarker, Inflammation Enhancer (IE). IE is an autoimmune disease factor - together with TNF, IE deteriorates inflammatory diseases such as sepsis and leads to high incidence of fatality. The lab is focusing on elucidating the pathway of IE that leads to inflammation. Diagnostic methods as well as treatments are also in development.
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ADVANCED THERAPEUTICSno. 11 (2023)
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Pathogens (Basel, Switzerland)no. 6 (2023): 817-817
FRONTIERS IN IMMUNOLOGY (2023)
Qing Zhang, Xiong Lu, Liang Gao, Siyu Tao, Yinghua Ge, Daocheng Cui,Renying Zhu,Wenshu Lu,Jian Wang,Shisong Jiang
Lina Zhang, Xinyi Shi,Qing Zhang,Zhilei Mao,Xiaoyu Shi,Jun Zhou, Aili Jian,Renying Zhu,Shisong Jiang,Wenshu Lu
Jian Wang, Yang Xiang,Shisong Jiang, Hongchang Li, Caviezel Flurin,Suporn Katawatin,Monchai Duangjinda
crossref(2021)
Jian Wang, Yang Xiang,Shisong Jiang, Hongchang Li, Flurin Caviezel,Suporn Katawatin,Monchai Duangjinda
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