基本信息
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职业迁徙
个人简介
Research synopsis
Our interests lie in the communication between different cell types of the immune system, specifically the mechanisms controlling cellular trafficking, multicellular organization and lymphoid organ architecture.
The lymph node is a highly organized and tightly controlled environment. The dynamic nature of lymph node swelling and contraction is critical to all immune responses and is not well understood.
We want to understand the processes involved in lymph node swelling/expansion, and how the interplay between immune cells and non-haematopeotic stromal cells is key to this process. By studying lymph node-dynamics we can learn about the control of immune responses. In addition, the lymph node as an experimental model is hugely relevant to the interplay between immune cells and stroma in settings such as tumours.
There are many parallels in the function of fibroblastic reticular cells (FRCs) of lymphoid tissues and tumour-associated fibroblasts. Taking lessons from the cell-cell interactions in the lymph node may provide novel avenues for tumour immunotherapy.
Our interests lie in the communication between different cell types of the immune system, specifically the mechanisms controlling cellular trafficking, multicellular organization and lymphoid organ architecture.
The lymph node is a highly organized and tightly controlled environment. The dynamic nature of lymph node swelling and contraction is critical to all immune responses and is not well understood.
We want to understand the processes involved in lymph node swelling/expansion, and how the interplay between immune cells and non-haematopeotic stromal cells is key to this process. By studying lymph node-dynamics we can learn about the control of immune responses. In addition, the lymph node as an experimental model is hugely relevant to the interplay between immune cells and stroma in settings such as tumours.
There are many parallels in the function of fibroblastic reticular cells (FRCs) of lymphoid tissues and tumour-associated fibroblasts. Taking lessons from the cell-cell interactions in the lymph node may provide novel avenues for tumour immunotherapy.
研究兴趣
论文共 43 篇作者统计合作学者相似作者
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BIOTECHNOLOGY JOURNALno. 1 (2024): e2300359-e2300359
OPEN BIOLOGYno. 5 (2023): 220377-220377
biorxiv(2022)
Jing Zhao,Sungwook Jung,Xiaofei Li,Lushen Li,Vivek Kasinath,Hengcheng Zhang, Said N Movahedi, Ahmad Mardini,Gianmarco Sabiu, Yoonha Hwang,Vikas Saxena,Yang Song,
TRENDS IN IMMUNOLOGYno. 9 (2021): 782-794
iScienceno. 9 (2021): 102976-11
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