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The impact of Schuster's work is noted via contributions in the fields of microbiology and genomics. He is included as one of the top 2% of most influential sceintists in 2019, according to an annually compiled list published by Stanford University. Schuster is also recognized as a pioneer of the next-generation sequencing (NGS) era, after having published a landmark study in ScienceExpress on 20th December 2005 on “Metagenomics and Paleogenomics of mammoth remains,” which was re-published in Science magazine in spring 2006 (4). This study followed the company 454 Life Sciences’ demonstration of emulsion PCR / pyrosequencing technology in September of the same year (5) and as such represents the first example of addressing a biological problem with NGS technology. Applying the emerging NGS technology to ancient DNA research, together with the use of novel DNA reservoirs (hair) (6), eventually led to the field of paleo-population genomics. This enabled the comparison of 18 complete mammoth mitochondrial genomes (mt genome) to those of a single Indian and single African Elephant mt genome sequence (7). The largely expanded sample number of specimens from an extinct species allowed studying mammoth populations across a time frame of 50,000 years (7). Using the same approach, the first sequences of an extinct marsupial were generated, thereby demonstrating that now extinct species display a reduced genetic diversity before their demise (Tasmanian Tiger, (Thylacinus cynocephalus); Tasmanian devil, (Sarcophilus harrisii)) (8). The genomics analysis of museum specimens was a further adopted to avian species, such as the Moa (9), thereby opening new possibilities for the use of vast collections in national archives for paleo-population genomics studies. The emerging field was coined by Schuster as “Museomics”, referring to museum genomics (10,11,12).
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Building and Environment (2024): 111264
Joao Felipe M. Salgado,Balakrishnan N. V. Premkrishnan,Elaine L. Oliveira,Vineeth Kodengil Vettath, Feng Guang Goh, Xinjun Hou,Daniela I. Drautz-Moses,Yu Cai,Stephan C. Schuster, Ana Carolina M.
biorxiv(2024)
ACS NANOno. 22 (2023): 23132-23143
Hie Lim Kim,Tanghua Li,Namrata Kalsi, Hung Tran The Nguyen,Timothy A. Shaw,Khai C. Ang,Keith C. Cheng,Aakrosh Ratan,W. Richard Peltier,Dhrubajyoti Samanta, Mahesh Pratapneni,Stephan C. Schuster,
Communications biologyno. 1 (2023): 150-10
Dorrain Low, Kai Xuan Tee, Oliver Meldrum,Giuseppe D’Agostino,Hye Jin Kim,Alicia Kang,Rikky Purbojati,Lakshmi Chandrasekaran,Daniela Drautz-Moses,Yifan Yang, Bobby Cheon, Aimee Elizabeth,
Current Developments in Nutritionno. Supplement_1 (2022): 1020-1020
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