views: 241
Information
Professor
Sign in to view more
Experience
Sign in to view more
Education
Sign in to view more
Bio
Lippard studies biological interactions involving metal ions, focusing on reactions and physical and structural properties of metal complexes. Such complexes can be useful as cancer drugs and as models for the active sites of metalloproteins. Metal ions also promote key biological reactions as signaling agents; metal complexes can be employed to sense biological signaling agents.
Lippard is an extramural faculty member of MIT’s David H. Koch Institute for Integrative Cancer Research and is well known for his work on the mechanism of the anti-cancer drug cisplatin, which contains platinum and is in first line therapy for many cancers. His lab is currently working on designing more effective platinum anti-tumor agents. Recently these studies have been extended to include additional third row transition elements including osmium and rhenium, complexes of which have the ability to destroy cancer stem cells thought to be responsible for tumor recurrence and metastasis.
Lippard is an extramural faculty member of MIT’s David H. Koch Institute for Integrative Cancer Research and is well known for his work on the mechanism of the anti-cancer drug cisplatin, which contains platinum and is in first line therapy for many cancers. His lab is currently working on designing more effective platinum anti-tumor agents. Recently these studies have been extended to include additional third row transition elements including osmium and rhenium, complexes of which have the ability to destroy cancer stem cells thought to be responsible for tumor recurrence and metastasis.
Research Interests
Papers
Sort
By YearBy Citation
Add Paper

View All
Ego Network
D-Core
Co-Author
Author Statistics
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn