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个人简介
Our translational human microbiome research program focuses on gastrointestinal and airway microbiome interactions with host immunity that promote or prevent development/maintenance of chronic inflammatory disease. Taking a "populations to molecules" approach we leverage the microbiome to determine the origins of childhood allergy and asthma and the early life molecular and cellular drivers of immune dysfunction that lead to childhood disease development. We also leverage human population studies and clinical trials to gain insights into the role of the gut microbiome in inflammatory bowel disease. Our studies allow us to develop rationally designed microbial therapeutics, leading to the founding of Siolta Therapeutics which is currently testing a lead product developed in our lab for the prevention of childhood allergy and asthma.
研究兴趣
论文共 374 篇作者统计合作学者相似作者
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Karin C Wu,Kathryn E McCauley,Susan V Lynch,Renuka R Nayak,Nicole J King,Sheena Patel, Tiffany Y Kim, Katherine Condra,Doug Fadrosh, Dat Nguyen,Din L Lin,Kole Lynch,
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research (2024)
Jonathan L. Golob,Tomiko T. Oskotsky,Alice S. Tang, Alennie Roldan,Verena Chung,Connie W. Y. Ha,Ronald J. Wong,Kaitlin J. Flynn, Antonio Parraga-Leo, Camilla Wibrand,Samuel S. Minot,Boris Oskotsky,
Kathryn E. McCauley,Juliana Durack,Kole V. Lynch,Douglas W. Fadrosh,Kei E. Fujimura, Faith Vundla,Mustafa Özçam, Petra LeBeau, Agustin Caltroni, Preston Burns,Hoang T. Tran,Leonard B. Bacharier,
Journal of Allergy and Clinical Immunology (2024)
GUT MICROBESno. 1 (2024): 2290661-2290661
Metabolitesno. 4 (2023): 510-510
Ryan Rampersaud, Chhedi Gupta,Connie Ha, Gwyneth Wu,Victor Reus,Susan Lynch,Synthia Mellon,Owen Wolkowitz
NEUROPSYCHOPHARMACOLOGY (2023): 248-249
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Frontiers in pediatrics (2023): 1155852-1155852
Nature medicineno. 11 (2023): 2793-2804
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