基本信息
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职业迁徙
个人简介
Takaomi C. Saido, born in 1959, (PhD, University of Tokyo School of Pharmaceutical
Science, 1988) started as a professional tenured scientist at Tokyo Metropolitan Institute
of Medical Science and worked on calpain, calcium-activated neutoral protease, brain
ischemia and Alzheimer’s disease (1998); joined RIKEN Brain Science Institute as Head
of Laboratory for Proteolytic Neuroscience (1997); started also to serve as Director for
the Group of Chemical Neuroscience in RIKEN BSI (2008). The aim of our research is to
establish cause-and-effect relationship and to clarify the mechanism of Aβ amyloidosisinduced
tauopathy and neurodegeneration in Alzheimer’s disease.
Awards and honors:
1985 Rotary International Fellowship。
1995 Young Investigator Award, Japanese Biochemical Society。
2002 Journal of Biochemistry Excellent Paper Prize。
2003 BSI Flagship Prize。
2003 Neuroscience Research Excellent Paper Prize。
2004 Outstanding contributor award, Alzheimer Research Forum。
2007 Toshihiko Tokizane Memorial Award。
Publications:
1. Toyoshima, S. Saido, T.C., Makishima, F., Osawa, T. (1983). Induction of increased
calcium uptake in liposomes having membrane proteins of chicken erythrocytes by Sadenosylmethionine.
Biochem. Biophys. Res. Commun. 114, 1126-1131.
2. Seki, H., Saido, T.C., Iseki, K., Whitney, F., Wong, S. (1984). Uptake kinetics of
micro-organisms in the sulfuretum of Saanich Inlet, British Columbia, Canada.
Arch. Hydrobiol., 100, 73-82.
3. Saido, T.C., Toyoshima, S., Osawa, T. (1987). Protein-Ocarboxylmethyltransferase
from cytosol and membranes of chicken erythrocytes. J.
Biochem. 102, 319-326.
4. Magae, J., Osada, H., Fujiki, H., Saido, T.C., Suzuki, K., Nagai, K., Yamasaki, M.,
Isono, K. (1990). Morphological changes of human myeloid leukemia K562 cells
by a protein phosphatase inhibitor, tautomycin. Proc. Japan Acad. 66, 209-212.
5. Osada, S., Mizuno, K., Saido, T.C., Akita, Y., Suzuki, K., Kuroki, T., Ohno, S.
(1990). A phorbol ester receptor/protein kinase, nPKCη, a new member of the protein kinase C family predominantly expressed in lung and skin. J. Biol. Chem.
265, 22434-22440.
研究兴趣
论文共 681 篇作者统计合作学者相似作者
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Lulu Jiang, Rebecca Roberts,Melissa Wong,Lushuang Zhang, Chelsea Joy Webber, Jenna Libera, Zihan Wang, Alper Kilci, Matthew Jenkins, Alejandro Rondón Ortiz, Luke Dorrian,Jingjing Sun,
Frontiers in Neuroscience (2024)
Lulu Jiang, Rebecca Roberts,Melissa Wong,Lushuang Zhang, Chelsea Joy Webber, Jenna Libera, Zihan Wang, Alper Kilci, Matthew Jenkins, Alejandro Rondón Ortiz, Luke Dorrian,Jingjing Sun,
Frontiers in neuroscience (2024): 1372297-1372297
FRONTIERS IN AGING NEUROSCIENCE (2024): 1361847-1361847
Helen Xuexia Huang,Paolo Inglese, Jiabin Tang, Riad Yagoubi,Goncalo D. S. Correia, Verena M. Horneffer-van der Sluis,Stephane Camuzeaux,Vincen Wu,Maksym V. Kopanitsa,Nanet Willumsen,Johanna S. Jackson,Anna M. Barron,
JOURNAL OF NEUROCHEMISTRY (2024)
Frontiers in Aging Neuroscience (2024): 1361847-1361847
biorxiv(2024)
Neurobiology of Aging (2024)
Takeru Nagayama,Sosuke Yagishita,Megumi Shibata, Akiko Furuno,Takashi Saito,Takaomi C. Saido,Shuji Wakatsuki,Toshiyuki Araki
Neuroscience Research (2024)
Farjana Parvin, Samuel Haglund, Bettina Wegenast-Braun,Mathias Jucker, Takashi Saito,Takaomi C Saido, K Peter R Nilsson,Per Nilsson, Sofie Nyström,Per Hammarström
ACS chemical neuroscience (2024)
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