基本信息
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职业迁徙
个人简介
Our studies of protein synthesis are focused on three main areas:
Translation GTPases
The GTPases eIF2 and eIF5B promote, respectively, the first and final steps in translation initiation.
eIF2a Phosphorylation
We are studying how the function of eukaryotic translation initiation factor 2 (eIF2) is regulated by phosphorylation, focusing on determinants of substrate recognition by the eIF2α protein kinases and the structure and regulation of these enzymes.
eIF5A
The factor eIF5A was originally identified by its ability to stimulate the yield (endpoint) of methionyl-puromycin synthesis, a model assay for first peptide bond synthesis.
研究兴趣
论文共 171 篇作者统计合作学者相似作者
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Genes & developmentno. 11-12 (2023): 474-489
Nucleic acids researchno. 13 (2023): 6899-6913
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Pedro Gonzalez-Menendez,Ira Phadke,Meagan E. Olive,Kathy L. McGraw,Jessica Platon,Julien Papoin,Hongxia Yan,Marie Daumur,Franciane Paul,Raghavendra Mirmira, Axel Joly, Jeremy Galtier,
biorxiv(2022)
Cellno. 24 (2022): 4474-4487.e17
Ivaylo P Ivanov,James A Saba,Chen-Ming Fan, Ji Wang, Andrew E Firth,Chune Cao,Rachel Green,Thomas E Dever
biorxiv(2021)
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