Timothy K. Lu(盧冠達)
副教授
Department of Biological Engineering
Massachusetts Institute of Technology;Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology;Senti Biosciences;Engine Biosciences;Tango Therapeutics;BiomX;Winged Concepts;Synlogic, Inc.;Eligo Biosciences;Corvium
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基本信息
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个人简介
Our research focuses on using synthetic biology and systems biology tools to engineer gene networks from the bottoms-up and to decipher natural gene networks from the top-down. We have developed high-throughput platforms for building and studying gene networks. These approaches have been applied to therapeutically relevant contexts. For example, we have engineered synthetic viruses to combat antibiotic resistant, genetically modified probiotics to treat inflammatory bowel disease in the gut, and next-generation viral therapies for cancer. In addition, we have used these technologies to study genetic interactions and potential targets for combinatorial therapy against antibiotic-resistant bacteria, cancer, and neurodegenerative diseases.
研究兴趣
论文共 246 篇作者统计合作学者相似作者
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Nature Communicationsno. 1 (2024): 1-17
Alba Gonzalez, Enping Hong, Gozde Yucel, Elizabeth Leitner, Pearley Chinta,Han Deng, Ian Li,Alice Lam, Abla Bakir,Brandon Lee, Papia Chakraborty, Carmina Blanco,
CANCER RESEARCHno. 7 (2023)
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Derrick Lee,Han Deng,Marcus Gainer,Chen-Ting Lee,Assen Roguev,Niran Almudhfar,Mengxi Tian,Alice Lam,Michelle Hung, Andrew Banicki, Lawrence Naitmazi, Yongshuai Li,
Journal for ImmunoTherapy of Cancerno. Suppl 1 (2023)
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Qi Cai,Sarah Warren, Violena Pietrobon,Markus Maeurer, Lei S Qi,Timothy K Lu, Marc J Lajoie,David Barrett,David F Stroncek, Francesco M Marincola
Cancer cellno. 10 (2023): 1689-1695
Chen-Ting Lee, Michelle Hung, Andrew Banicki, Wenqi Song, Niran Almudhfar,Deepika Kaveri,Priscilla Wong, Lawrence Naitmazi, Marcela Guzman,Alice Lam, Gozde Yucel,Timothy Lu,
CANCER RESEARCHno. 7 (2023)
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Journal for ImmunoTherapy of Cancerno. Suppl 1 (2023)
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Philip Lee,Assen Roguev, Cesar Juarez,Michelle Hung,Frances D Liu, Yin Yin Chong,Russell M Gordley,Mark Tomishima, Jessica M Haverkamp, Panos Douvaras, Alex Danza, Monika Avina,
Journal for ImmunoTherapy of Cancerno. Suppl 1 (2023)
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Nicholas Frankel, Ippolito Imani Caradonna,Marcus A. Gainer, Junjie Tony Hua,Brian S. Garrison,Russell M. Gordley,Timothy K. Lu
MOLECULAR THERAPYno. 4 (2023): 665-665
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