particularly interested in the signalling pathways that mediate normal thyroid growth and function and are dysregulated in thyroid cancer and goitre. With a longstanding interest in investigating the repression of the iodide transporter NIS in thyroid cancer Vicki has recently identified a possible new therapeutic strategy to improve critical radioiodine treatment in thyroid tumours. She is currently interested in exploring the possibility of applying these strategies to induce radioiodine uptake in other tumour types such as breast cancer. These investigations include in vitro culture systems, animal models and human tissue to combine fundamental and translational research.