William E. Dowdle - Department of Biochemistry and Biophysics and Cardiovascular Research Institute, University of California

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论文共 40 篇作者统计合作学者相似作者

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Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques

Xiaomeng Hu,Kathy White, Ari G. Olroyd, Rowena DeJesus, Antonia A. Dominguez,William E. Dowdle, Annabelle M. Friera,Chi Young, Frank Wells,Elaine Y. Chu, Cade Ellis Ito, Harini Krishnapura,

Nature Biotechnology（2024）

引用5浏览0WOSNATURE引用

Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases

Robert A Craig,Javier De Vicente,Anthony A Estrada,Jianwen A Feng,Katrina W Lexa, Mark J Canet,William E Dowdle, Rebecca I Erickson, Brittany N Flores, Patrick C G Haddick,Lesley A Kane,Joseph W Lewcock,

Journal of medicinal chemistry（2024）

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DNL343 is an investigational CNS penetrant eIF2B activator that prevents and reverses the effects of neurodegeneration caused by the Integrated Stress Response

Ernie Yulyaningsih,Jung H. Suh, Melania H. Fanok,Roni Chau,Hilda Solanoy,Ryan Takahashi,Anna I. Bakardjiev,Isabel Becerra, N. Butch Benitez,Chi-Lu Chiu,Sonnet S Davis,William E. Dowdle,

bioRxiv (Cold Spring Harbor Laboratory) (2023)

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Hypoimmune anti-CD19 chimeric antigen receptor T cells provide lasting tumor control in fully immunocompetent allogeneic humanized mice

Xiaomeng Hu, Karl Manner,Rowena DeJesus,Kathy White,Corie Gattis,Priscilla Ngo,Christopher Bandoro,Eleonore Tham,Elaine Y. Chu,Chi Young,Frank Wells, Ronald Basco,

Nature communicationsno. 1 (2023): 2020-14

引用9浏览0WOSNATURE引用

Abstract 4091: Engineered hypoimmune CAR T cells provide lasting tumor control in immunocompetent allogeneic humanized mice even with re-challenge

Xiaomeng Hu, Pascal Beauchesne, Karl Manner,Corie Gattis, Priscilla Ngo, Rowena De Jesus, Ramya Ankala,Chi Young,Frank Wells,Lindong Weng,Kathy White,William E. Dowdle,

Cancer Researchno. 7_Supplement (2023): 4091-4091

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Human hypoimmune primary pancreatic islets avoid rejection and autoimmunity and alleviate diabetes in allogeneic humanized mice

Xiaomeng Hu,Corie Gattis,Ari G. Olroyd, Annabelle M. Friera,Kathy White,Chi Young,Ron Basco, Meghan Lamba,Frank Wells, Ramya Ankala,William E. Dowdle, August Lin,

Science Translational Medicineno. 691 (2023): eadg5794-eadg5794

引用10浏览0WOSSCIENCE引用

Overcoming Immunological Barriers for "Off-the-Shelf" iPSC-Derived Islets

Xiaomeng Hu, Kathy White, Ari G. Olroyd, Rowena Dejesus, Antonia Dominguez,William E. Dowdle, Elaine Y. L. Chu, Annabelle Friera,Chi Young, Frank Wells,Trevor McGill, Michael Rukstalis,

Diabetes（2022）

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Engineered Hypoimmune CAR T Cells Provide Lasting Tumor Control in Fully Immunocompetent Allogeneic Humanized Mice

Xiaomeng Hu, Pascal Beauchesne, Karl Manner,Corie Gattis,Priscilla Ngo, Rowena De Jesus,Chi Young,Frank Wells,Lindong Weng,Kathy White,William E Dowdle,Aaron Foster,

Blood（2022）

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Efficient and Specific Multi-Locus Editing of Allogeneic CAR T Cells for Hypoimmunity during Large Scale Manufacture Using Cas12b

Christina Chaivorapol, Pascal Beauchesne, Rowena De Jesus,William E Dowdle, Xiaoyu Chen, Alison Bayley, Yunjiang Qiu, Andrew Birnberg, Yu Zheng, Antonino Montalbano,Angela Liu, Misbah Zafar,

Blood（2022）

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Engineered hypoimmune allogeneic CAR T cells as potential off-the-shelf CAR T cell immunotherapies

Xiaomeng Hu,Kathy White,Corie Gattis,Ryan Clarke,Sam Landry,Ron Basco,Eleonore Tham,Emily Luo,Andrew Tucker,Christopher Bandoro,Elaine Chu,Chi Young,

CANCER RESEARCHno. 12 (2022)

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