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职业迁徙
个人简介
My research is focused on the field of cardiovascular disease and cardiac tissue engineering. An important component of my current thesis research is to better understand the complex bidirectional cardiomyocyte-fibroblast interactions potentially involving complex bidirectional signaling through direct cell-cell contacts, paracrine actions, and/or extracellular matrix-mediated effects. I have been combining the use of diseased mouse models and tissue engineering techniques to systematically assess how disease-induced changes in fibroblast phenotype alter the electrical and mechanical function of cardiomyocyte in vitro and determine the underlying molecular mechanisms. Through this and future studies, I hope to discover novel fibroblast-related targets leading to more efficient drug or gene therapies for heart disease.
研究兴趣
论文共 10 篇作者统计合作学者相似作者
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Vaibhao Janbandhu, Vikram Tallapragada,Ralph Patrick,Yanzhen Li,Dhanushi Abeygunawardena,David T Humphreys,Ella M M A Martin,Alexander O Ward,Osvaldo Contreras,Nona Farbehi,Ernestene Yao, Junjie Du,
Cell stem cellno. 2 (2021): 281-297.e12
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