基本信息
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职业迁徙
个人简介
Research in Yi Zhang's laboratory is focused on epigenetic modifications, particularly DNA methylation and covalent histone modifications, which play an important role in regulating chromatin dynamics, and therefore have a significant impact on gene expression. They have investigated how epigenetic modification-mediated dynamic changes in chromatin structure affect gene expression, cell lineage commitment, stem cell pluripotency, and stem cell self-renewal. In addition, they have studied mis-regulation of epigenetic factors and how that contributes to the development of diabetes, neurological diseases, and cancer.
The Zhang lab also investigates the epigenetic mechanisms in embryonic development, stem cell reprogramming, β-cell regeneration, and drug addiction. Yi Zhang's long-term goal is to apply what his group has learned in basic research to studies of human diseases.
The Zhang lab also investigates the epigenetic mechanisms in embryonic development, stem cell reprogramming, β-cell regeneration, and drug addiction. Yi Zhang's long-term goal is to apply what his group has learned in basic research to studies of human diseases.
研究兴趣
论文共 373 篇作者统计合作学者相似作者
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Journal of Biological Chemistryno. 3 (2024)
biorxiv(2024)
Vikrant Kumar Sinha,Yi Zhang,Longxia Xu, Yu-Wen Chen,Sarah Picaud,Mohamad Zandian, Soumi Biswas,Panagis Filippakopoulos,Shu-Ping Wang,Xiaobing Shi,Tatiana G. Kutateladze
Journal of molecular biologypp.168212, (2023)
Aritra Bhattacherjee,Chao Zhang, Brianna R. Watson,Mohamed Nadhir Djekidel, Jeffrey R. Moffitt,Yi Zhang
Zenodo (CERN European Organization for Nuclear Research) (2023)
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Journal of cellular and molecular medicine (2023)
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Yi Zhang, Yanhui Li,Yang Liu,Hongzhi Wang,Yingli Chen,Bing Zhang, Meiqi Song,Lei Song,Qinchao Ding,Jiannan Qiu, Mingjian Fan, Lihui Qu,
Metabolism: clinical and experimental (2023): 155656-155656
GENOMICS PROTEOMICS & BIOINFORMATICSno. 3 (2023): 649-661
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