In September 2005, Professor Chen joined the faculty at Washington University in St. Louis. He has a number of awards including the Microsoft Research New Faculty Fellowship and the Department of Energy Early Career Principal Investigator Award. Professor Chen also serves his professional societies as a programming committee member, fund reviewer and National Science Foundation review panelist. He is an IEEE Fellow.

Yixin Chen's research interests are in the general areas of artificial intelligence, machine learning, data mining, optimization, and computational biomedicine. He is particularly interested in human-AI collaboration, deep learning, and their applications.