Soft, stretchable and conductive biointerfaces for bio-hybrid tactile sensing investigation
Living Machines'13 Proceedings of the Second international conference on Biomimetic and Biohybrid Systems(2013)
摘要
In this work we present the design, fabrication and characterization of polymer-based soft, stretchable and conductive biointerfaces for achieving both mechanical stimulation of cells and recording of their response. These biointerfaces represent the very first step for investigating potential bio-hybrid tactile sensing approaches. Cells transform mechanical stimuli into biological and biochemical signals (mechanotransduction): modifications on cell mem-brane structure lead to a final change in membrane electric potential. Therefore, an efficient way to quantify cellular response to mechanical stimuli is to evaluate the impedance variation of cells due to externally applied forces.
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关键词
impedance variation,cell mem-brane structure lead,mechanical stimulation,mechanical stimulus,cellular response,biochemical signal,potential bio-hybrid tactile,conductive biointerfaces,membrane electric potential,final change
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