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Calpain 3, the “gatekeeper” of proper sarcomere assembly, turnover and maintenance

Neuromuscular Disorders, no. 12 (2008): 913-921

被引用116|浏览7
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Calpain 3 is a member of the calpain family of calcium-dependent intracellular proteases. Thirteen years ago it was discovered that mutations in calpain 3 (CAPN3) result in an autosomal recessive and progressive form of limb girdle muscular dystrophy called limb girdle muscular dystrophy type 2A. While calpain 3 mRNA is expressed at high ...更多

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