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Strategies for successful recombinant expression of disulfide bond-dependent proteins in Escherichia coli

Microbial Cell Factories, no. 1 (2009): 26-18

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Disulfide Bond Isomerase Domoic Acid Recombinant Antibody Leader Peptide

Abstract

Bacteria are simple and cost effective hosts for producing recombinant proteins. However, their physiological features may limit their use for obtaining in native form proteins of some specific structural classes, such as for instance polypeptides that undergo extensive post-translational modifications. To some extent, also the production...More

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Ario de Marco

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