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Epigenetics in cancer.
CARCINOGENESIS, no. 1 (2010): 27-36
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Epigenetic mechanisms are essential for normal development and maintenance of tissue-specific gene expression patterns in mammals. Disruption of epigenetic processes can lead to altered gene function and malignant cellular transformation. Global changes in the epigenetic landscape are a hallmark of cancer. The initiation and progression o...更多
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