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The Ap1-Dependent Secretion Of Galectin-1 By Reed - Sternberg Cells Fosters Immune Privilege In Classical Hodgkin Lymphoma

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, no. 32 (2007): 13134-13139

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Classical Hodgkin lymphomas (cHLs) contain small numbers of neoplastic Reed-Sternberg (RS) cells within an extensive inflammatory infiltrate that includes abundant T helper (Th)-2 and T regulatory (T-reg) cells. The skewed nature of the T cell infiltrate and the lack of an effective host antitumor immune response suggest that RS cells use...更多

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