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Synchronous Alterations Of Wnt And Epidermal Growth Factor Receptor Signaling Pathways Through Aberrant Methylation And Mutation In Non-Small Cell Lung Cancer

CLINICAL CANCER RESEARCH, no. 20 (2007): 6087-6092

Cited: 71|Views25
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Abstract

Purpose: The Wnt and epidermal growth factor receptor (EGFR) signaling pathways play crucial roles in the pathogenesis of a variety of malignant tumors. Although the details of each cascade are understood, very little is known about their collective effects in non -small cell lung cancer (NSCLC).Experimental Design: A total of 238 NSCLC s...More

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