PRMT6 diminishes HIV-1 Rev binding to and export of viral RNA

Retrovirology, no. 1 (2006): 93-15

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BACKGROUND: The HIV-1 Rev protein mediates nuclear export of unspliced and partially spliced viral RNA through interaction with the Rev response element (RRE) by means of an arginine rich motif that is similar to the one found in Tat. Since Tat is known to be asymmetrically arginine dimethylated by protein arginine methyltransferase 6 (PR...更多

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