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A Coactivator Trap Identifies Nono (P54(Nrb)) As A Component Of The Camp-Signaling Pathway

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, no. 51 (2007): 20314-20319

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academic.microsoft.com pubmed.ncbi.nlm.nih.gov

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transcription signal transduction cell-based screen RNA polymerase II transducer of regulated cAMP response element-binding protein

摘要

Signal transduction pathways often use a transcriptional component to mediate adaptive cellular responses. Coactivator proteins function prominently in these pathways as the conduit to the basic transcriptional machinery. Here we present a high-throughput cell-based screening strategy, termed the "coactivator trap," to study the functiona...更多

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