Re-Evaluating Cell-Cycle Regulation by E2Fs
Cell, no. 5 (2006): 871-874
Activation of E2F transcription factors is thought to drive the expression of genes essential for the transition of cells from G1 to S phase and for the initiation of DNA replication. However, this textbook view of E2Fs is increasingly under challenge. Here we discuss an alternative model for how E2Fs may work.
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