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Control of DNA Strand Displacement Kinetics Using Toehold Exchange

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, no. 47 (2009): 17303-17314

Cited: 668|Views18
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Abstract

DNA is increasingly being used as the engineering material of choice for the construction of nanoscale circuits, structures, and motors. Many of these enzyme-free constructions function by DNA strand displacement reactions. The kinetics of strand displacement can be modulated by toeholds, short single-stranded segments of DNA that colocal...More

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