P53 And Retinoid Chemoprevention Of Oral Carcinogenesis

CANCER RESEARCH, no. 1 (1995): 16-19

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We studied p53 protein's pattern of expression, association with retinoid response or resistance, and modulation by retinoid intervention in oral premalignancy. These p53 analyses were included in a prospective trial of the retinoid isotretinoin (1.5 mg/kg/day for 3 months) in 40 patients (45 oral premalignant lesions), Seven nonsmoking s...更多

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