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PP2A regulates the pro-apoptotic activity of FOXO1.

The Journal of biological chemistry, no. 12 (2008): 7411-7420

Cited by: 79|Views3
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Abstract

FOXO1, a member of the evolutionarily conserved forkhead family of transcription factors, regulates expression of a number of genes that play critical roles in cell cycle and apoptosis. A pivotal regulatory mechanism of FOXO is reversible phosphorylation, catalyzed by kinases and phosphatases. Phosphorylation of FOXO1 is associated with 1...More

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