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Cellular Notch responsiveness is defined by phosphoinositide 3-kinase-dependent signals.

BMC cell biology, no. 1 (2006): 10-10

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Notch plays a wide-ranging role in controlling cell fate, differentiation and development. The PI3K-Akt pathway is a similarly conserved signalling pathway which regulates processes such as differentiation, proliferation and survival. Mice with disrupted Notch and PI3K signalling show phenotypic similarities during haematopoietic cell dev...更多

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