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Radioprotection Of Mice By Recombinant Rat Stem-Cell Factor

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, no. 20 (1992): 9464-9468

Cited: 102|Views29
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Abstract

Treatment with recombinant rat stem cell factor (rSCF) protects mice from the lethal effects of irradiation. Mice treated with a single dose of rSCF prior to irradiation of up to 1150 rads [given as a split dose (1 rad = 0.01 Gy)] resulted in >80% long-term survival, whereas a single injection given after the last dose of irradiation was ...More

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