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Biochemical And Functional Characterization Of Orai Proteins
JOURNAL OF BIOLOGICAL CHEMISTRY, no. 22 (2007): 16232-16243
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Stimulation of immune cells triggers Ca2+ entry through store-operated Ca2+ release-activated Ca2+ channels, promoting nuclear translocation of the transcription factor NFAT. Through genome-wide RNA interference screens in Drosophila, we and others identified olf186-F (Drosophila Orai, dOrai) and dStim as critical components of store-oper...更多
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