Covariance of maximum likelihood evolutionary distances between sequences aligned pairwise.
BMC evolutionary biology, no. 1 (2008): 179-179
The estimation of a distance between two biological sequences is a fundamental process in molecular evolution. It is usually performed by maximum likelihood (ML) on characters aligned either pairwise or jointly in a multiple sequence alignment (MSA). Estimators for the covariance of pairs from an MSA are known, but we are not aware of any...更多
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