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Genomic Islands of Uropathogenic Escherichia coli Contribute to Virulence

JOURNAL OF BACTERIOLOGY, no. 11 (2009): 3469-3481

Cited: 69|Views28
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Abstract

Uropathogenic Escherichia coli (UPEC) strain CFT073 contains 13 large genomic islands ranging in size from 32 kb to 123 kb. Eleven of these genomic islands were individually deleted from the genome, and nine isogenic mutants were tested for their ability to colonize the CBA/J mouse model of ascending urinary tract infection. Three genomic...More

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