Differentiated evolutionary rates in alternative exons and the implications for splicing regulation.

BMC evolutionary biology, no. 1 (2006): 50-50

Cited: 120|Views26
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Abstract

Alternatively spliced exons play an important role in the diversification of gene function in most metazoans and are highly regulated by conserved motifs in exons and introns. Two contradicting properties have been associated to evolutionary conserved alternative exons: higher sequence conservation and higher rate of non-synonymous substi...More

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