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Rolling Circle Dna-Replication In-Vitro By A Complex Of Herpes-Simplex Virus Type 1-Encoded Enzymes

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, no. 22 (1994): 10665-10669

Cited: 81|Views22
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Abstract

Extracts of insect cells infected with baculoviruses recombinant for the herpes simplex virus 1 (HSV-1)-encoded enzymes that are required for its replication can promote the rolling circle replication of circular plasmid templates. Replication is independent of a HSV-1 origin of replication (ori(s)) or the HSV-1 origin binding protein and...More

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