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Ribosomal binding to the internal ribosomal entry site of classical swine fever virus
RNA, no. 12 (2000): 1791-1807
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Most eukaryotic mRNAs require the cap-binding complex eIF4F for efficient initiation of translation, which occurs as a result of ribosomal scanning from the capped 5' end of the mRNA to the initiation codon. A few cellular and viral mRNAs are translated by a cap and end-independent mechanism known as internal ribosomal entry. The internal...More
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