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Mechanism of promoter melting by the xeroderma pigmentosum complementation group B helicase of transcription factor IIH revealed by protein-DNA photo-cross-linking.

MOLECULAR AND CELLULAR BIOLOGY, no. 21 (2000): 8168-8177

Cited: 82|Views30
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Abstract

The p89/xeroderma pigmentosum complementation group B (XPB) ATPase-helicase of transcription factor IIH (TFIIH) is essential for promoter melting prior to transcription initiation by RNA polymerase II (RNA-PII). By studying the topological organization of the initiation complex using site-specific protein-DNA photo-cross-linking, we have ...More

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