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Whole Genome Amplification And High-Throughput Allelotyping Identified Five Distinct Deletion Regions On Chromosomes 5 And 6 In Microdissected Early-Stage Ovarian Tumors

CANCER RESEARCH, no. 10 (2001): 4169-4174

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Investigation of genetic changes in tumors by loss of heterozygosity is a powerful technique for identifying chromosomal regions that may contain tumor suppressor genes. In this study, we determined allelic loss on chromosomes 5 and 6 in 29 primary early-stage epithelial ovarian carcinomas including 3 microscopically identified adenocarci...More

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