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Cyclic Nucleotide-Gated Channels Contribute to the Cholinergic Plateau Potential in Hippocampal CA1 Pyramidal Neurons

JOURNAL OF NEUROSCIENCE, no. 22 (2001): 8707-8714

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academic.microsoft.com pubmed.ncbi.nlm.nih.gov

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seizureacetylcholinemuscarinic receptorscGMPguanylate cyclase更多(2+)

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Plateau potentials are prolonged membrane depolarizations that are observed in hippocampal pyramidal neurons when spiking and Ca2+ entry occur in combination with muscarinic receptor activation. In this study, we used whole-cell voltage clamping to study the current underlying the plateau potential and to determine the cellular signaling ...更多

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