Developmental Regulation Of Eed Complex Composition Governs A Switch In Global Histone Modification In Brain

JOURNAL OF BIOLOGICAL CHEMISTRY, no. 13 (2007): 9962-9972

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Originally discovered as epigenetic regulators of developmental gene expression, the Polycomb (PcG) and trithorax (trxG) group of proteins form distinct nuclear complexes governing post-translational modification of histone tails. This study identified a novel, developmentally regulated interface between Eed and Mll, pivotal constituents ...更多

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